Chromatin state predict transcriptional regulatory circuitry

Download: TranscriptH3K36me3 level, H3K4me1 matrix

Transcript H3K36me3 level approximate gene expression level and characterize phenotypically-related cell groups. Clusters of coherently regulated transcripts indicate functional annotations related to the respective cell and tissue groups (Left ).

H3K4me1 are more cell -specific than H3K36me3 and provides more precise definition of cell-specific regulation. More than half of H3K4me1 sites identified in this resource are specific to in vivo tissues, which are particularly valuable for human genetics (right)